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First International Spinal Cord Injury Treatments & Trials Symposium
第一屆國際脊髓損傷治療與臨床試驗交流會

17-20 Dec, 2005  Faculty of Medicine, The University of Hong Kong

17 December 2005 (Saturday)
Time Session Venue
07:45 08:30 Registration & Tea Reception Lift Lobby & Foyer
08:30 09:00 Opening Ceremony Lecture Theatre
09:00 09:40 Plenary Lecture 1: Recovery of the Spinal Cord Functions after Spinal Cord Injury: Neurocontrol Aspects
Chair: Paul TAM (Hong Kong SAR, China)
Speaker: Milan DIMITRIJEVIC (Houston, USA)
Lecture Theatre
09:40 10:10 Keynote Lecture 1: Surgical Management of Acute Spinal Cord Trauma
Chair: John LEONG (Hong Kong SAR, China)
Speaker: Charles TATOR (Ontario, Canada)
Lecture Theatre
10:10 10:30 Coffee Break and Poster Viewing Foyer
10:30 12:30 Session 1A: Care of Spinal Cord Injury
Session Chair: Charles TATOR (Ontario, Canada) and Wai-Sang POON (Hong Kong SAR, China)
  • Predicting Outcome in Traumatic Spinal Cord Injury
    - John DITUNNO (Philadelphia, USA
  • Orthopedic Management for the Chronic Spinal Cord Injuried
    - Keith LUK (Hong Kong SAR, China)
  • Maximizing the Rehabilitation after Spinal Cord Injury
    - John McDONALD (Maryland, USA)
  • Neurosurgical Management of Chronic Spinal Cord Injury
    - James GUEST (Miami, USA)
  • Sexual Function and Spinal Cord Injury
    - Claes HULTLING (Stockholm, Sweden)
  • Application of Biological Chitin Tubes in Spinal Cord Injury Research
    - Baoguo JIANG (Beijing, China)
Lecture Theatre
12:30 14:00 Lunch Break and Poster Viewing Exhibition Area
14:00 14:30 Keynote Lecture 2: Treatment of Spinal Cord Injury: Thirty Years Review and Conclusion
Chair: Jizong ZHAO (Beijing, China)
Speaker: Shaoting XU (Beijing, China)

Lecture Theatre

14:30 15:30

Session 1B: Care of Spinal Cord Injury
Session Chair: John McDONALD (Maryland, USA) and Jianjun LI (Beijing, China)

  • Surgical Management of Acute Cervical Spinal Cord Injury in the Presence of Head Injury
    - Wai-Sang POON (Hong Kong SAR, China)
  • Rehabilitation Management of Spinal Cord Injury in China Present Situation: Prospects for 21st Century
    - Jianjun LI (Beijing, China)
  • Spinal Cord Injuries: 15 Years of Outcome Analysis
    - Jizong ZHAO (Beijing, China)
Lecture Theatre
15:30 16:00 Coffee Break and Poster Viewing Foyer

16:00 17:00

  • Orthopedic Management of Spinal Cord Injury in China
    - Zhuojing LUO (Xi'an, China)
  • Orthopedic Management to Improve the Functional Outcome in Spinal Cord Injury
    - Yat-Wa WONG (Hong Kong SAR, China)
  • Reinnervation for Neurogenic Bladder and Bowel after Spinal Cord Injury: Historic Review
    - Chuanguo XIAO (Wuhan, China)
Lecture Theatre
17:00 18:00 Panel Discussion: How to Maximize the Functional Outcome in Spinal Cord Injury Rehabilitation
Panel Chair: Keith LUK and Yat-Wa WONG (Hong Kong SAR)
Lecture Theatre
18:30 20:00 Welcome Reception Foyer and Garden

18 December 2005 (Sunday)
Time Session Venue
08:30 09:00 Registration and Poster Viewing Lift Lobby & Foyer
09:00 09:40 Plenary Lecture 2: Evidence-based Strategies for Identifying Effective Therapies for Spinal Injury Systematic Review and Large Simple Trials
Chair: Wise YOUNG (New Jersey, USA)
Speaker: Michael BRACKEN (New Haven, USA)
Lecture Theatre
09:40 10:10 Keynote Lecture 3: The Present Status of Basic Research on SCI in Mainland China
Chair: Kwok-Fai SO (Hong Kong SAR, China)
Speaker: Gong JU (Xi'an, China)
Lecture Theatre
10:10 10:30 Coffee Break and Poster Viewing Foyer
10:30 12:30

Session 2A: Clinical Trials in China
Session Chair: Ying-Shing CHAN (Hong Kong SAR, China) and Baoguo JIANG (Beijing, China)

  • Basic and Clinical Researches of Olfactory Ensheathing Cells for Spinal Cord Injury
    - Hongyun HUANG (Beijing, China)
  • Transplantation of Olfactory Ensheathing Cells for the Treatment of Spinal Cord Injury Experimental and Clinical Observation
    - Tiansheng SUN (Beijing, China)
  • Olfactory Ensheathing Cells: Migratory Property after being Transplanted in Spinal Cord
    - Huiyong SHEN (Guangzhou, China) Intraspinal Transplantation of Human Fetal Schwann Cells in Paralysed Patients
    - Hui ZHU (Kunming, China)
  • Clinical Study on Repair of Injured Spinal Cord by Transplants of Autologous Bone Marrow Stem Cell
    - Yongfu ZHANG (Zhengzhou, China)
  • The Mechanism of Immediate Neurofunction Restoration after Subdural Lysis of Old Incomplete Spinal Cord Injury
    - Shaocheng ZHANG (Shanghai, China)
Lecture Theatre

12:30 14:00

Lunch Break and Poster Viewing

Exhibition Area
14:00 14:30 Keynote Lecture 4: Spinal Cord Repair with Acidic FGF as a Treatment for the Patients with Chronic Paraplegia and Quadriplegia
Chair: Shew-Ping CHOW (Hong Kong SAR, China)
Speaker: Henrich CHENG (Taipei, Taiwan)
Lecture Theatre
14:30 15:30 Session 2B: Clinical Trials around the World
Session Chair: James GUEST (Miami, USA) and Mai-Har SHAM (Hong Kong SAR, China)
  • Development of Valid Spinal Cord Injury Clinical Trial Guidelines
    - John STEEVES (Vancouver, Canada)
  • A Phase 1 Controlled Trial of Autologous Olfactory Ensheathing Cell Transplantation in Human Spinal Cord Injury
    - Adrian NOWITZKE (Woolloongabba, Australia)
  • Thoracolumbar Fracture Management: Anterior Approach
    - Dadi JIN (Guangzhou, China)
Lecture Theatre
15:30 16:00 Coffee Break and Poster Viewing Foyer
16:00 17:00
  • Treatment of Complete Spinal Cord Injury by Autologous Bone Marrow Cell Transplantation and Administration of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)
    - Yoon HA (Inchon, Korea)
  • Cell Technologies in the Complex Therapy of Spinal Cord Injury: from Trial to Clinical Practice
    - Andrey BRYUKHOVETSKIY (Moscow, Russia)
  • Self Assembling Nano Material for CNS Lesion Repair
    - Rutledge ELLIS-BEHNKE (Cambridge, USA)
Lecture Theatre
17:00 18:00 Panel Discussion: What Have We Learnt from the First Generation of Spinal Cord Injury Clinical Trials
Panel Chair: Wise YOUNG (New Jersey, USA)
Lecture Theatre

19 December 2005 (Monday)
Time Session Venue
08:30 09:00 Registration and Poster Viewing Lift Lobby & Foyer
09:00 09:40 Plenary Lecture 3: Advances in the Treatments of Spinal Cord Injury
Chair: Grace TANG (Hong Kong SAR, China)
Speaker: Wise YOUNG (New Jersey, USA)
Lecture Theatre
09:40 10:10 Keynote Lecture 5: Transplantation of Olfactory Ensheathing Cells in Rat
Chair: Siu-Wa TANG (Hong Kong SAR, China)
Speaker: Geoffrey RAISMAN (London, United Kingdom)
Lecture Theatre
10:10 10:30 Coffee Break and Poster Viewing Foyer
10:30 12:30 Session 3A: Experimental Acute Therapies
Session Chair: Geoffrey RAISMAN (London, United Kingdom) and Daisy SHUM (Hong Kong SAR, China)
  • Combined Treatment of Lithium Chloride and Chondroitinase ABC
    - Kwok-Fai SO (Hong Kong SAR, China)
  • Acute Transplantation of Radial Glial Neural Stem Cells Promotes Recovery after Spinal Cord Contusion
    - Martin GRUMET (New Jersey, USA)
  • Use of hESC-derived Oligodendroglial Progenitors in the Treatment of Spinal Cord Injury
    - Hans KEIRSTEAD (Irvine, USA)
  • The Nogo66 Receptor and CNS Axon Regeneration: New Treatment Strategies for Spinal Cord Injury?
    - Daniel LEE (Cambridge, USA)
  • LINGO-1 and Its Role in Axon Regeneration
    - Sha MI (Cambridge, USA)
  • Genetic Mechanisms of Methylprednisolone Protection of Oligodendrocytes from SCI-induced Death
    - Chung HSU (Taipei, Taiwan)
Lecture Theatre
12:30 14:00 Lunch Break and Poster Viewing Exhibition Area
14:00 14:30 Keynote Lecture 6: Towards Spinal Cord Repair Combinatorial Strategies Involving Neuroprotection and Axonal Regeneration
Chair: John STEEVES (Vancouver, Canada)
Speaker: Xiao-Ming XU (Louisville, USA)
Lecture Theatre
14:30 15:30 Session 3B: Experimental Chronic Therapies
  • Application of Biological Chitin Tubes in Spinal Cord Injury Research
    - Baoguo JIANG (Beijing, China)
  • Multimechanistic Repair of Injured Spinal Cord: White Matter vs. Gray Matter
    - Yang TENG (Boston, USA)
  • Secondary Degeneration Reduced by Inosine after Spinal Cord Injury in Rats
    - Siwei YOU (Xi'an, China)

Lecture Theatre

15:30 16:00 Coffee Break and Poster Viewing Foyer
16:00 17:00
  • Schwann's Cells and Spinal Cord Injury Basic and Clinical Studies
    - Shiqing FENG (Tianjin, China)
  • Dog Sciatic Nerve Regeneration across a 30-mm Defect Bridged by an Artificial Nerve Graft
    - Xiaosong GU (Nantong, China)
  • Axonal Regeneration of Lower Motor Neuron
    - Wutian WU (Hong Kong SAR, China)
Lecture Theatre
17:00 8:00 Panel Discussion: The Role of Combinational Therapy in Spinal Cord Injury Therapy
Panel Chair: Wutian WU (Hong Kong SAR, China)
Lecture Theatre
18:30 22:00 Gala Dinner HK Academy of
Medicine Jockey
Club Building

20 December 2005 (Tuesday)
Time Session Venue
08:30 09:00 Registration and Poster Viewing Lift Lobby & Foyer
09:00 09:40 Plenary Lecture 4: Obstacles and Opportunities for Collaborations among Academia, Industry and Government
Chair: Karen LAM (Hong Kong SAR, China)
Speaker: Johan KARLBERG (Hong Kong SAR, China)
Lecture Theatre
09:40 11:00 Session 4A: Spinal Cord Clinical Trials Design, Quality and Ethics
Session Chair: Tiansheng SUN (Beijing, China) and Edwin HUI (Hong Kong SAR, China)
  • From Discovery to Clinical Trials
    - Paul VANHOUTTE (Hong Kong SAR)
  • Study Designs and Outcome Measures in Spinal Cord Injury Clinical Trials
    - Andrew BLIGHT (New York, USA)
  • Quality Assurance Measures within the China SCI Clinical Trial Network
    - Johan KARLBERG (Hong Kong SAR, China)
  • Ethical and Legal Concerns of Stem Cell Research
    - Edwin HUI (Hong Kong SAR, China)
Lecture Theatre
11:00 11:30 Coffee Break and Poster Viewing Foyer
11:30 12:30

Panel Discussion: Will China Spinal Cord Injury Clinical Trial Data be Accepted by Overseas Regulatory Authorities?
Panel Chair: Paul VANHOUTTE (Hong Kong SAR)

Lecture Theatre
12:30 14:00 Lunch Break and Poster Viewing Exhibition Area
14:00 15:30 Panel Discussion: Most Promising and Feasible Therapy for Spinal Cord Injury Clinical Trials
Panel Chair: Wise YOUNG (New Jersey, USA) and Kwok-Fai SO (Hong Kong SAR, China)

Lecture Theatre

15:30 16:00 Summary of the Symposium
- Wise YOUNG (New Jersey, USA)
Lecture Theatre
 
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